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Bird Flu Vaccine Developed for Dairy Calves

Bird Flu Vaccine Developed for Dairy Calves


By Jamie Martin

As cases of bird flu continue rising across dairy herds, researchers have developed a new mRNA vaccine to protect dairy calves from the H5N1 virus.

The vaccine is currently under early testing and shows promise in preventing transmission through infected milk.

Scientists from the University of Pennsylvania and the USDA published their findings on bioRxiv, a preprint research platform.

The results indicate that vaccinated calves may be protected from catching the virus through their mother’s infected milk—a key breakthrough in safeguarding young cattle.

Idaho has emerged as the most affected state, reporting 17 infected herds in May alone. The rapid spread has raised national concern, especially for food security and the stability of the dairy industry.

Though this experimental vaccine has not yet been tested in adult cows, experts remain optimistic. Dr. David Pate, former CEO of St. Luke’s Health System, explained the importance of this research in improving food safety. “It's not a total solution, that the more we learn about these vaccines and how we can adapt them to stop these transmissions is going to make our food sources safer,” he said.

The new mRNA-based approach mirrors the strategy used successfully in COVID-19 vaccines. It allows quicker adaptation and production, giving scientists a powerful tool against rapidly evolving viruses like H5N1.

While this calf-specific vaccine moves toward peer review and further testing, it highlights a broader need for continued investment in agricultural health tools.

The recent cancellation of federal plans to develop human flu vaccines—including for avian flu—underscores the urgency of innovation in animal protection.

The progress seen in this study offers a glimpse of future solutions that can protect livestock, secure milk supplies, and support farmers during health crises. Continued research and funding are critical to ensuring long-term success.

Photo Credit: gettyimages-jessicahyde


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